IL-4R is expressed on alpha and beta cells of human pancreata

Author:

Rajendran Sakthi,Graef Madeleine,Chu Tiffany,von Herrath Matthias

Funder

Network for Pancreatic Organ donors with Diabetes

JDRF

Leona M. & Harry B. Helmsley Charitable Trust

La Jolla Institute for Immunology

National Institute of Health

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference13 articles.

1. Interferon-gamma-induced interferon regulatory factor-1 (IRF-1) expression in rodent and human islet cells precedes nitric oxide production;Flodstrom;Endocrinology,1997

2. Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes;Bradley;J. Immunol.,1999

3. Decreased IL-4 production in new onset type I insulin-dependent diabetes mellitus;Berman;J. Immunol.,1996

4. Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice;Mueller;J. Exp. Med.,1996

5. Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice;Rapoport;J. Exp. Med.,1993

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