Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion-Reference-Cited by-同舟云学术

Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

Published:1981-07 Issue:2 Volume:101 Page:440-446
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Okamoto Shosuke,Hijikata Akiko,Kikumoto Ryoji,Tonomura Shinji,Hara Hiroto,Ninomiya Kunihiro,Maruyama Akira,Sugano Mamoru,Tamao Yoshikuni

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference11 articles.

1. Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases

2. Aromatic esters which inhibit plasmin or thrombin by formation of relatively stable acyl enzymes

3. Synthetic inhibitors of serine proteinases XVI. Influence of 3- and 4-amidinobenzyl derivatives on the formation and action of thrombin

4. Differential specificities of thrombin, plasmin and trypsin with regard to synthetic and natural substrates and inhibitors

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