The epoxide hydrolase catalyzed hydrolysis of trans-3-bromo-1,2-epoxycyclohexane. A direct proof for a general base catalyzed mechanism of the enzymatic hydration-Reference-Cited by-同舟云学术

The epoxide hydrolase catalyzed hydrolysis of trans-3-bromo-1,2-epoxycyclohexane. A direct proof for a general base catalyzed mechanism of the enzymatic hydration

Published:1981-10 Issue:3 Volume:102 Page:838-844
ISSN:0006-291X
Container-title:Biochemical and Biophysical Research Communications
language:en
Short-container-title:Biochemical and Biophysical Research Communications

Author:

Bellucci Giuseppe,Berti Giancarlo,Ferretti Maria,Marioni Franco,Re Franca

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference20 articles.

1. Enzymic hydration of [18O]epoxides. Role of nucleophilic mechanisms

2. Mechanism of catalysis for the hydration of substituted styrene oxides by hepatic epoxide hydrase

3. Hepatic microsomal epoxide hydrase. Involvement of a histidine at the active site suggests a nucleophilic mechanism.

4. Hepatic microsomal epoxide hydrolase. Mechanistic studies of the hydration of K-region arene oxides.

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