Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-α inhibitor

Author:

Clements John M,Cossins Judy A,Wells Graham M.A,Corkill Dominic J,Helfrich Karen,Wood L.Mike,Pigott Rod,Stabler Gary,Ward George A,Gearing Andrew J.H,Miller Karen M

Publisher

Elsevier BV

Subject

Neurology (clinical),Neurology,Immunology,Immunology and Allergy

Reference44 articles.

1. Alvord, E.C., Kiess, M.W. and Suckling, A.J. (1984) Experimental Allergic Encephalomyelitis: A Useful Model of Multiple Sclerosis. Alan R. Liss, New York.

2. Baker, D., Butler, D., Scallon, B.J., O'Neill, J.K., Turk, J.L. and Feldmann, M. (1994) Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins. Eur. J. Immunol. 24, 2040–2048.

3. Baragi, V., Fliszar, C.J., Conroy, M.C., Ye, Q.-Z., Shipley, J.M. and Welgus, H.G. (1994) Contribution of the C-terminal truncated domain of metalloproteinases to binding by TIMP: C-terminal truncated stromelysin and matrilysin exhibit equally compromised affinities as compared to full-length stromelysin. J. Biol. Chem. 269, 12692–12697.

4. Benvenuto, R., Paroli. M., Buttinelli. C., Franco. A., Barnaba. V., Fieschi, C. and Balsano F. (1991) Tumour necrosis factor-alpha synthesis by cerebrospinal fluid-derived T-cell clones from patients with multiple sclerosis. Clin. Exp. Immunol. 84, 97–102.

5. Birkedal-Hansen, H., Moore, W.G.I., Bodden, M.K., Windsor, L.J., Birkedal-Hansen, B., DeCarlo, A. and Engler, J.A. (1993) Matrix metalloproteinases: A review. Crit. Rev. Oral Biol. Med. 4, 197–250.

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