Linkage of boronated polylysine to glycoside moieties of polyclonal antibody; boronated antibodies as potential delivery agents for neutron capture therapy 1 1Abbreviations: BNCT, Boron neutron capture therapy; BPL, Boronated poly-DL-lysine; BSA, Bovine serum albumin; DMBA, p-Dimethylaminobenzaldehyde; DMF, Dimethylformamide; DMSO, Dimethyl sulfoxide; DTT, Dithiothreitol; FTSC, Fluorescein thiosemicarbazide; HRP, Horseradish peroxidase; IgG, Immunoglobulin-G; IRMA, Immunoradiometric assay; LET, Linear energy transfer; MB-hydrazide, m-Maleimidobenzoyl hydrazide; MW, Molecular weight; PBS, Phosphate buffered saline; PL, Poly-DL-lysine; SDS-PAGE, Sodium n-Dodecyl Sulfate Polyacrylamide Gel Electrophoresis; SPDP, N-Succinimidyl-3-(2 pyridyldithio) propionate; Sulfo-MBS, m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester; TRIZMA®, Tris (hydroxymethyl) aminomethane; TSH, Thyroid stimulating hormone.

Author:

Novick Sara,Quastel Michael R,Marcus Stephanie,Chipman David,Shani Gad,Barth Rolf F,Soloway Albert H

Publisher

Elsevier BV

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Molecular Medicine

Reference45 articles.

1. New horizons for therapy based on the boron neutron capture reaction;Hawthorne;Mol. Med. Today,1998

2. Boron neutron uptake therapy of brain tumors;Barth;Neurosurgery,1999

3. The chemistry of neutron capture therapy;Soloway;Chem. Rev.,1998

4. Advances in neutron capture therapy (vol I). Medicine and Physics & II, Chemistry and Biology;Larsson,1997

5. Frontiers in neutron capture therapy;Hawthorne,2001

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