Multiscale deep neural network based analysis of FDG-PET images for the early diagnosis of Alzheimer’s disease

Author:

Lu DonghuanORCID,Popuri Karteek,Ding Gavin WeiguangORCID,Balachandar Rakesh,Beg Mirza FaisalORCID

Funder

National Science Engineering Research Council (NSERC)

Canadian Institutes of Health Research (CIHR)

Michael Smith Foundation for Health Research (MSFHR)

Brain Canada

Pacific Alzheimer Research Foundation (PARF)

Alzheimer’s Disease Neuroimaging Initiative (ADNI)

National Institutes of Health

DOD

ADNI

Department of Defense

National Institute on Aging

National Institute of Biomedical Imaging and Bioengineering

AbbVie

Alzheimer’s Association

Alzheimer’s Drug Discovery Foundation

Araclon Biotech

BioClinica, Inc.

Biogen

Bristol-Myers Squibb Company

CereSpir, Inc.

Cogstate

Eisai Inc.

Elan Pharmaceuticals, Inc.

Eli Lilly and Company

EuroImmun

F. Hoffmann-La Roche Ltd

Genentech, Inc.

Fujirebio

GE Healthcare

IXICO Ltd.

Janssen Alzheimer Immunotherapy Research & Development, LLC.

Johnson & Johnson Pharmaceutical Research & Development LLC.

Lumosity

Lundbeck

Merck & Co., Inc.

Meso Scale Diagnostics, LLC.

NeuroRx Research

Neurotrack Technologies

Novartis Pharmaceuticals Corporation

Pfizer Inc.

Piramal Imaging; Servier

Takeda Pharmaceutical Company

Transition Therapeutics

Canadian Institutes of Health Research

Publisher

Elsevier BV

Subject

Computer Graphics and Computer-Aided Design,Health Informatics,Computer Vision and Pattern Recognition,Radiology Nuclear Medicine and imaging,Radiological and Ultrasound Technology

Reference38 articles.

1. Abadi, M., Agarwal, A., Barham, P., Brevdo, E., Chen, Z., Citro, C., Corrado, G. S., Davis, A., Dean, J., Devin, M., Ghemawat, S., Goodfellow, I., Harp, A., Irving, G., Isard, M., Jia, Y., Jozefowicz, R., Kaiser, L., Kudlur, M., Levenberg, J., Mané, D., Monga, R., Moore, S., Murray, D., Olah, C., Schuster, M., Shlens, J., Steiner, B., Sutskever, I., Talwar, K., Tucker, P., Vanhoucke, V., Vasudevan, V., Viégas, F., Vinyals, O., Warden, P., Wattenberg, M., Wicke, M., Yu, Y., Zheng, X. (2015). TensorFlow: Large-scale machine learning on heterogeneous systems. Software available from tensorflow.org, URL http://tensorflow.org/.

2. The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the national institute on aging-Alzheimer’s association workgroups on diagnostic guidelines for Alzheimer’s disease;Albert;Alzheimer’s Dementia,2011

3. 2011 Alzheimer’s disease facts and figures.;Alzheimer’s;Alzheimer’s Dementia,2011

4. Computing large deformation metric mappings via geodesic flows of diffeomorphisms;Beg;Int. J. Comput. Vis.,2005

5. Practical recommendations for gradient-based training of deep architectures;Bengio,2012

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