Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib**The investigators had full access to the data and complete control over the design, conduct analysis, interpretation, and description of the study. The sponsor of the study had no role in study design, data collection, data analysis, data interpretation, or in writing the report. The views expressed are those of the investigators alone.

Author:

White William B,Faich Gerald,Borer Jeffrey S,Makuch Robert W

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference22 articles.

1. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis—The CLASS study;Silverstein;JAMA,2000

2. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis;Bombardier;N Engl J Med,2000

3. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2;McAdam;Proc Natl Acad Sci USA,1999

4. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids;Catella-Lawson;J Pharmacol Exp Ther,1999

5. Role of prostacyclin in the cardiovascular response of thromboxane A2;Cheng;Science,2002

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