Increased efficacy of antileishmanial antisense phosphorothioate oligonucleotides in Leishmania amazonensis overexpressing ribonuclease H11Abbreviations: RNase H, ribonuclease H; S-oligo, phosphorothioate-modified oligodeoxyribonucleotide; LUAS, anti-luciferase antisense S-oligo; LUS, S-oligo complementary to LUAS; ASM, S-oligo antisense to Leishmania miniexon; SSM, S-oligo complementary to ASM; HIFBS, heat-inactivated fetal bovine serum; TbRH1, Trypanosoma brucei RNase H1 gene; RACE, rapid amplification of cDNA ends; MBSA, maleylated bovine serum albumin; ODN, oligodeoxyribonucleotide; PCR, polymerase chain reaction; and DMPC, dimyristoyl phosphatidylcholine.-Reference-Cited by-同舟云学术

Increased efficacy of antileishmanial antisense phosphorothioate oligonucleotides in Leishmania amazonensis overexpressing ribonuclease H11Abbreviations: RNase H, ribonuclease H; S-oligo, phosphorothioate-modified oligodeoxyribonucleotide; LUAS, anti-luciferase antisense S-oligo; LUS, S-oligo complementary to LUAS; ASM, S-oligo antisense to Leishmania miniexon; SSM, S-oligo complementary to ASM; HIFBS, heat-inactivated fetal bovine serum; TbRH1, Trypanosoma brucei RNase H1 gene; RACE, rapid amplification of cDNA ends; MBSA, maleylated bovine serum albumin; ODN, oligodeoxyribonucleotide; PCR, polymerase chain reaction; and DMPC, dimyristoyl phosphatidylcholine.

Published:2001-02 Issue:4 Volume:61 Page:467-476
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Mishra Manjari,Bennett Jabbar R.,Chaudhuri Gautam

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

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