Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2′,3′,5′-tri-O-acetyluridine, a prodrug of uridine-Reference-Cited by-同舟云学术

Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2′,3′,5′-tri-O-acetyluridine, a prodrug of uridine

Published:2000-08 Issue:3 Volume:60 Page:427-431
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Ashour Osama M,Naguib Fardos N.M,Panzica Raymond P,Al Safarjalani Omar N,el Kouni Mahmoud H

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference39 articles.

1. Uridine rescue from the lethal toxicity of 5-fluorouracil in mice;Klubes;Cancer Chemother Pharmacol,1982

2. High dose 5-fluorouracil with delayed uridine “rescue” in mice;Martin;Cancer Res,1982

3. Use of uridine rescue to enhance the antitumor selectivity of 5-fluorouracil;Klubes;Cancer Res,1983

4. In vitro biochemical and in vivo biological studies of the uridine ‘rescue’ of 5-fluorouracil;Peters;Br J Cancer,1988

5. Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-l-aspartate, methotrexate, and leucovorin;Seiter;Cancer,1993

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