Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-2′-deoxyadenosine

Author:

Bontemps Françoise,Delacauw Anne,Cardoen Sabine,Van Den Neste Eric,Van Den Berghe Georges

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo;Carson;Proc Natl Acad Sci USA,1980

2. Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes;Seto;J Clin Invest,1985

3. Biochemical pharmacology of 2-chlorodeoxyadenosine in malignant human hematopoietic cell lines and therapeutic effects of 2-bromodeoxyadenosine in drug combinations in mice;Avery;Cancer Res,1989

4. 2-Chloro-2′-deoxyadenosine;Delannoy;Blood Rev,1996

5. Nucleoside analogs;Plunkett,1997

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