Selective binding of trisamine-modified phosphorothioate antisense DNA to target mRNA improves antisense activity and reduces toxicity
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry,Biophysics
Reference36 articles.
1. Phosphorothioate analogues of oligodeoxyribonucleotides: novel inhibitors of replication and cytopathic effect of human immunodeficiency virus (HIV);Matsukura;Proc. Natl. Acad. Sci. USA,1987
2. Regulation of virul expression of human immunodeficiency virus in vitro by antisense phosphorothioate oligodeoxynucleotides against Rev (art/tris) in chronicaly infected cells;Matsukura;Proc. Natl. Acad. Sci. USA,1989
3. Antisense oligonucleotide: a new therapeutic principle;Uhlmann;Chem. Rev.,1990
4. Current concept in antisense design;Milligan;J. Med. Chem.,1993
5. Progress in antisense oligonucleotide therapeutics;Crooke;Annu. Rev. Pharmacol. Toxicol.,1996
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