1. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11;Kawato;Cancer Res,1991
2. Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase;Satoh;Biol Pharm Bull,1994
3. Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11);Potter;Cancer Res,1998
4. In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors;Kojima;J Clin Invest,1998
5. Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy;Danks;Clin Cancer Res,1999