Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells11Abbreviations: AC, adenylate cyclase; AP, activator protein; AS-O, antisense oligonucleotide; cAMP, 3′,5′-adenosine-cyclic monophosphate; cGMP, 3′,5′-guanosine-cyclic monophosphate; EHNA, erythro-9-(2-hydroxy-3-nonyl)adenine; GAM, goat anti-mouse IgG polyclonal antibody; IBMX, 3-isobutyl-1-methylxanthine; IL-13, interleukin-13; 8-methoxymethyl-IBMX, 8-methoxymethyl-3-isobutyl-1-methylxanthine; NS-O, nonsense oligonucleotide; PCR, polymerase chain reaction; PDE, cyclic nucleotide phosphodiesterase; PHA, phytohemagglutinin; RT, reverse transcription; and TCR, T cell receptor.