MDR1 bicistronic vectors: analysis of selection stringency, amplified gene expression, and vector stability in cell lines 2 2Abbreviations:MDR1, human multidrug resistance-1 gene; Pgp, P-glycoprotein; neo, bacterial neomycin resistance gene; PCR, polymerase chain reaction; and NPT, neomycin phosphotransferase.-Reference-Cited by-同舟云学术

MDR1 bicistronic vectors: analysis of selection stringency, amplified gene expression, and vector stability in cell lines 2 2Abbreviations:MDR1, human multidrug resistance-1 gene; Pgp, P-glycoprotein; neo, bacterial neomycin resistance gene; PCR, polymerase chain reaction; and NPT, neomycin phosphotransferase.

Published:2001-09 Issue:6 Volume:62 Page:693-704
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Kane Susan E,Matsumoto Linda,Metz Marianne Z,Donohue Cecile A,Lingeman Robert G,Lin Sharon W,Doroshow James H

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference54 articles.

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4. A retrovirus carrying an MDR1 cDNA confers multidrug resistance, and polarized expression of P-glycoprotein in MDCK cells;Pastan;Proc Natl Acad Sci USA,1988

5. Expression of a full-length cDNA for the human “MDR1” gene confers resistance to colchicine, doxorubicin, and vinblastine;Ueda;Proc Natl Acad Sci USA,1987

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