A simple and sensitive differential digestion method to analyze adeno-associated virus residual host cell proteins by LC-MS

Author:

Hu Yunli,Hu Mengqi,Ye Xiang,Wu Zhijie,Kang Jianming,Wong Christina,Palackal Nisha,Qiu Haibo,Li Ning

Publisher

Elsevier BV

Reference25 articles.

1. Adeno-associated virus vector as a platform for gene therapy delivery;Wang;Nat. Rev. Drug Discov.,2019

2. AAV manufacturing for clinical use: Insights on current challenges from the upstream process perspective;Dobrowsky;Curr. Opin. Biomed. Eng.,2021

3. Moving from the bench towards a large scale, industrial platform process for adeno-associated viral vector purification;Adams;Biotechnol. Bioeng.,2020

4. Analytics of host cell proteins (HCPs): lessons from biopharmaceutical mAb analysis for Gene therapy products;Bracewell;Curr. Opin. Biotech.,2021

5. Assessment of quality attributes for adeno-associated viral vectors;Tustian;Biotechnol. Bioeng.,2021

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