Optimization of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 metabolites in human biological fluids

Author:

Sprega Giorgia,Kobidze Giorgi,Lo Faro Alfredo Fabrizio,Pichini Simona,Farkas Tivadar,Tini Anastasio,Mskhiladze Antonina,Busardò Francesco Paolo,Chankvetadze Bezhan

Funder

Shota Rustaveli National Science Foundation

Publisher

Elsevier BV

Reference11 articles.

1. 〈https://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-is-the-scope-of-mdma-use-in-the-united-states〉.

2. 〈https://www.theguardian.com/australia-news/2023/jul/01/australian-psychiatrists-can-now-prescribe-mdma-and-psilocybin-who-can-access-them-and-how-do-they-work〉.

3. The role of metabolism in 3,4-(+)-methylenedioxyamphetamine and 3,4-(+)-methylenedioxymethamphetamine (ecstasy) toxicity;Monks;Ther. Drug Monit.,2004

4. The pharmacology and toxicology of “ecstasy” (MDMA) and related drugs;Kalant;CMAJ,2001

5. 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans;Steele;Addiction,1994

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