Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/−)-praeruptorin A, (+/−)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/−)-cis-khellactone, in rat plasma using online solid phase extraction–chiral LC–MS/MS-Reference-Cited by-同舟云学术

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Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/−)-praeruptorin A, (+/−)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/−)-cis-khellactone, in rat plasma using online solid phase extraction–chiral LC–MS/MS

Published:2014-01 Issue: Volume:88 Page:269-277
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Song Yuelin,Jing Wanghui,Yang Fengqing,Shi Zhan,Yao Meicun,Yan Ru,Wang Yitao

Funder

National Basic Research Program of China 973

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference35 articles.

1. Hydroxylation of R(+)- and S(−)-omeprazole after racemic dosing are different among the CYP2C19 genotypes;Shiohira;Pharm. Res.,2012

2. Tracking problems and possible solutions in the quantitative determination of small molecule drugs and metabolites in biological fluids using liquid chromatography–mass spectrometry;Bakhtiar;J. Pharmacol. Toxicol. Methods,2007

3. Drug binding to human alpha-1-acid glycoprotein in health and disease;Kremer;Pharmacol. Rev.,1988

4. Molecular aspects of ligand binding to serum albumin;Kragh-Hansen;Pharmacol. Rev.,1981

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