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High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug–plasma protein interactions

  • Published:2013-02 Issue: Volume:74 Page:205-212
  • ISSN:0731-7085
  • Container-title:Journal of Pharmaceutical and Biomedical Analysis
  • language:en
  • Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Vuignier Karine,Guillarme Davy,Veuthey Jean-Luc,Carrupt Pierre-Alain,Schappler Julie

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference59 articles.

1. Compilation of 222 drugs’ plasma protein binding data and guidance for study designs;Zhang;Drug Discov. Today,2012

2. A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition;Buur;Res. Vet. Sci.,2009

3. Predicting plasma protein binding of drugs: a new approach;Kratochwil;Biochem. Pharmacol.,2002

4. The importance of plasma protein binding in drug discovery;Trainor;Expert Opin. Drug Discov.,2007

5. Drug-Like Properties: Concepts, Structure Design and Methods;Kerns,2008

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