Development and validation of a HPLC–MS/MS method for the determination of phytolaccagenin in rat plasma and application to a pharmacokinetic study

Author:

Wei Fenghuan,Singh Ravi Shankar Prasad,Fueth Matthias,Swarts Steven,Okunieff Paul,Derendorf Hartmut

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference16 articles.

1. The Pharmacopeoia of People's Republic of China (Part I);Editorial Committee of Pharmacopoeia of Ministry of Health, PR China,2010

2. Studies on the structures of phytolaccasaponin B, E and G from the roots of Phytolacca americana L.;Suga;Chem. Pharm. Bull.,1978

3. Synthesis of novel derivatives of Esculentoside A and its aglycone phytolaccagenin, and evaluation of their haemolytic activity and inhibition of lipopolysaccharide-induced nitric oxide production;Gong;Chem. Biodivers.,2011

4. Anti-inflammatory effects of Esculentoside A;Zheng;Chin. J. Pharmacol. Toxicol.,1992

5. Effects of Esculentoside A on production of interleukin-1,2, and prostaglandin E2;Xiao;Acta Pharmacol. Sin.,2004

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