A validated LC–MS/MS method of total and unbound lenvatinib quantification in human serum for protein binding studies by equilibrium dialysis
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference10 articles.
1. E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition;Matsui;Int. J. Cancer,2008
2. Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase;Matsui;Clin. Cancer Res.,2008
3. Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models;Okamoto;Cancer Lett.,2013
4. A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours;Boss;Br. J. Cancer,2012
5. Phase I dose-escalation study and biomarker analysis of E7080 in patients with advanced solid tumors;Yamada;Clin. Cancer Res.,2011
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