A UHPLC–MS/MS method coupled with simple and efficient alkaline hydrolysis for free and total determination of conjugate nanomedicine: Pharmacokinetic and biodistribution study of poly (l-glutamic acid)-graft-methoxy poly (ethylene glycol)/combretastatin A4

Author:

Zeng Qiang,Liu Yali,Song Yonggui,Feng Bingwei,Xu Pengfei,Shan Baixi,Liao Zhou,Liu Kuangyi,Zhong Youbao,Chen Lai,Su Dan

Funder

National Natural Science Foundation of China

Jiangxi Province Nature Scientific Project

Jiangxi University of Traditional Chinese Medicine Graduate Innovation Fund

Laboratory Animal Science and Technology Center

Jiangxi University of Traditional Chinese Medicine

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

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