Identification and characterization of quinoline alkaloids from the root bark of Dictamnus dasycarpus and their metabolites in rat plasma, urine and feces by UPLC/Qtrap-MS and UPLC/Q-TOF-MS

Author:

Chang Kun,Gao Peng,Lu Ying-Yuan,Tu Peng-Fei,Jiang Yong,Guo Xiao-Yu

Funder

Ministry of Science and Technology of the People's Republic of China

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference33 articles.

1. Pharmacopoeia of People’s Republic of China;The Pharmacopoeia Commission of the P.R.C,2020

2. Quality standard study on Dictamni Cortex;Wang;J. Chin. Pharm. Sci.,2017

3. Pressurized liquid extraction followed by high-performance liquid chromatography for determination of seven active compounds in Cortex Dictamni;Jiang;J. Chromatogr. A,2006

4. Cortex dictamni-induced liver injury in mice: the role of P450-mediated metabolic activation of furanoids;Huang;Toxicol. Lett.,2020

5. The modulatory role of CYP3A4 in dictamnine-induced hepatotoxicity;Li;Front. Pharmacol.,2018

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