Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS-Reference-Cited by-同舟云学术

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Pharmacokinetics, oral bioavailability and metabolic analysis of solasodine in mice by dried blood spot LC-MS/MS and UHPLC-Q-Exactive MS

Published:2022-02 Issue: Volume:210 Page:114542
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Qu Mei,Xue Peng,Zhang Qi,Lu Tiantian,Liu Kun,Hu Bingying,Pang Jingjing,Xiao Qianqian,Xu Tongxin,Wang Quande,Cheng Zhongzhe

Funder

Natural Science Foundation of Shandong Province

Department of Science and Technology of Shandong Province

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference28 articles.

1. The naturally occurring steroid solasodine induces neurogenesis in vitro and in vivo;Lecanu;Neuroscience,2011

2. Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents;Chauhan;Pharm. Biol.,2011

3. Solasodine protects rat brain against ischemia/reperfusion injury through its antioxidant activity;Sharma;Eur. J. Pharmacol.,2014

4. Solasodine induces apoptosis, affects autophagy, and attenuates metastasis in ovarian cancer cells;Xu;Planta Med.,2017

5. Solasodine reverses stemness and epithelial-mesenchymal transition in human colorectal cancer;Zhuang;Biochem. Biophys. Res. Commun.,2018

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development and validation of a dried blood spots assay for metabolic profiling of ginsenosides using ultra-high performance liquid chromatography-mass spectrometry;Journal of Ethnopharmacology;2024-07

2. Nobiletin, an active component of Wenyang Yiqi Formula, alleviates constipation associated depression through targeting MAPT to inhibit the MAPK signaling pathway;Phytomedicine;2023-11

3. Bioactivities and chemical profiling comparison and metabolomic variations of polyphenolics and steroidal glycoalkaloids in different parts of Solanum nigrum L.;Phytochemical Analysis;2023-10-18

4. Comparative transcriptome analysis of different tissues of Solanum khasianum reveals candidate genes involved in steroidal glycoalkaloid biosynthesis;Physiologia Plantarum;2023-08

5. Potentiation of Antibiotic Action and Efflux Pump Inhibitory Effect on Staphylococcus aureus Strains by Solasodine;Antibiotics;2022-09-27

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