Liquid chromatography–tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776

Author:

Holleran Julianne L.,Parise Robert A.,Yellow-Duke Archibong E.,Egorin Merrill J.,Eiseman Julie L.,Covey Joseph M.,Beumer Jan H.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference7 articles.

1. Topoisomerase I inhibitors: camptothecins and beyond;Pommier;Nat. Rev. Cancer,2006

2. Novel indenoisoquinolines NSC 725776 and NSC 724998 produce persistent topoisomerase I cleavage complexes and overcome multidrug resistance;Antony;Cancer Res,2007

3. Indenoisoquinolines NSC 725776 and NSC 724998 inhibit angiogenesis: gamma-H2AX is potential pharmacologic biomarker;Kaur;Proc Am Assoc Cancer Res,2008

4. Determination of camptothecin analogs in biological matrices by high-performance liquid chromatography;Loos;Anticancer Drugs,2000

5. Bioanalytical liquid chromatographic method validation. A review of current practices and procedures;Rosing;J Liq Chromatogr Relat Technol,2000

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