High-throughput determination of octanol/water partition coefficients using a shake-flask method and novel two-phase solvent system

Author:

Morikawa GoORCID,Suzuka Chihiro,Shoji Atsushi,Shibusawa Yoichi,Yanagida Akio

Funder

Grant-in-Aid for Scientific Research (C)

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference34 articles.

1. Octanol–Water Partition Coefficients: Fundamentals and Physical Chemistry;Sangster,1996

2. Separation methods for estimating octanol–water partition coefficients;Poole;J. Chromatogr. B,2003

3. Determination of liquid–liquid partition coefficients by separation methods;Berthod;J. Chromatogr. A,2004

4. The octanol–water partition coefficient: strengths and limitations;Hermens;Environ. Toxicol. Chem.,2013

5. Mechanized determination of n-octanol/water partition contants using liquid–liquid segmented flow extraction;Danielsson;J. Pharm. Biomed. Anal.,1994

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