Evaluation of hepatic metabolism and pharmacokinetics of ibuprofen in rats under chronic hypobaric hypoxia for targeted therapy at high altitude-Reference-Cited by-同舟云学术

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Evaluation of hepatic metabolism and pharmacokinetics of ibuprofen in rats under chronic hypobaric hypoxia for targeted therapy at high altitude

Published:2016-03 Issue: Volume:121 Page:114-122
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Gola Shefali,Gupta Asheesh^ORCID,Keshri Gaurav K.,Nath Madhu,Velpandian Thirumurthy

Funder

Defence Research and Development Organization (DRDO), Ministry of Defence, Government of India

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference30 articles.

1. High altitude cerebral and pulmonary edema;Basnyat;Travel Med. Infect. Dis.,2005

2. Hypobaric hypoxia affects endogenous levels of U-keto acids in murine heart ventricles;Muhlinga;Biochem. Biophys. Res. Commun.,2006

3. Intermittent hypoxia has organ-specific effects on oxidative stress;Jun;Am. J. Physiol. Regul. Integr. Comp. Physiol.,2008

4. Active oxygen species in the liver of rats submitted to chronic hypobaric hypoxia;Costa;Am. J. Physiol.,1993

5. Acute hypoxia and cytochrome P450-mediated hepatic drug metabolism in humans;Jürgens;Clin. Pharmacol. Ther.,2002

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