In vitro and in vivo metabolic investigation of the Palbociclib by UHPLC-Q-TOF/MS/MS and in silico toxicity studies of its metabolites
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference20 articles.
1. Palbociclib (PD0332991)’a Selective and Potent Cyclin-Dependent Kinase Inhibitor: a review of pharmacodynamics and clinical development;Clark;JAMA Oncol.,2016
2. Palbociclib: a first-in-class CDK4/CDK6 inhibitor for the treatment of hormone-receptor positive advanced breast cancer;Lu;J. Hematol. Oncol.,2015
3. https://www.fda.gov/Drugs/InformationOnDrugs/ApprovedDrugs/ucm549978.htm.
4. Palbociclib a novel cyclin-dependent kinase inhibitor for hormone receptor–positive advanced Breast cancer;Mangini;Ann. Pharmacother.,2015
5. Quantitative analysis of PD 0332991 in mouse plasma using automated micro-sample processing and microbore liquid chromatography coupled with tandem mass spectrometry;Smith;J. Chromatogr. B,2011
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