Small volume rapid equilibrium dialysis (RED) measures effects of interstitial parameters on the protein-bound fraction of topical drugs
Author:
Funder
Bundesministerium für Verkehr, Innovation und Technologie
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference35 articles.
1. Plasma protein binding in drug discovery and development;Howard;Comb. Chem. High Throughput Screen.,2010
2. The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery;Smith;Nat. Rev. Drug Discov.,2010
3. Plasma protein binding: from discovery to development;Bohnert;J. Pharm. Sci.,2013
4. The bioanalytical challenge of determining unbound concentration and protein binding for drugs;Nilsson;Bioanalysis,2013
5. Drug-protein binding: a critical review of analytical tools;Vuignier;Anal. Bioanal. Chem.,2010
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