Structural characterization and in silico toxicity prediction of degradation impurities of roxadustat

Author:

Mahajan Rupali,Kumar Sanjeev,Parupalli Ramulu,Khemchandani Rahul,Kanchupalli Vinaykumar,Nanduri Srinivas,Samanthula GananadhamuORCID,Asthana Amit

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference26 articles.

1. Roxadustat: first global approval;Dhillon;Drugs,2019

2. Roxadustat: Uses, Interactions, Mechanism of Action | DrugBank Online, (n.d.). https://go.drugbank.com/drugs/DB04847 (accessed April 18, 2023).

3. Safety and effectiveness of roxadustat in dialysis-dependent patients with renal anemia: a hospital-based cohort study;Moussa;Cureus,2022

4. A Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free Tablet Formulation and Pediatric Azo Dye-free Mini-tablet Formulation Compared to a Single Dose of Azo Dye-containing Tablet Formulation in Heal, (n.d.). https://clinicaltrials.gov/ct2/show/NCT03960489?term=Roxadustat&recrs=e&draw=2&rank=9 (accessed April 20, 2023).

5. Detection by LC–MS/MS of HIF stabilizer FG-4592 used as a new doping agent: Investigation on a positive case;Buisson;J. Pharm. Biomed. Anal.,2016

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