Simultaneous determination of methotrexate and its polyglutamate metabolites in Caco-2 cells by liquid chromatography–tandem mass spectrometry
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference12 articles.
1. High-dose methotrexate: a critical reappraisal.
2. Methotrexate
3. Polyglutamation of methotrexate. Is methotrexate a prodrug?
4. Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis
5. Red Blood Cell Methotrexate Polyglutamate Concentrations in Inflammatory Bowel Disease
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1. Methotrexate Polyglutamates Analysis by Chromatography Methods in Biological Matrices: A Review;Analytical Sciences;2021-12-10
2. Plasma Distribution of Methotrexate and Its Polyglutamates in Pediatric Acute Lymphoblastic Leukemia: Preliminary Insights;European Journal of Drug Metabolism and Pharmacokinetics;2021-10-12
3. Simultaneous determination of erythrocyte methotrexate polyglutamates by a novel and simple HPLC‐MS/MS method with stable isotope‐labeled internal standards;Journal of Separation Science;2021-03-18
4. Molecular mechanism of action and pharmacokinetic properties of methotrexate;Molecular Biology Reports;2020-05-15
5. Organization of the intestinal mucosa and barriers to oral drug delivery;Nanotechnology for Oral Drug Delivery;2020
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