Method development and application of offline two-dimensional liquid chromatography/quadrupole time-of-flight mass spectrometry-fast data directed analysis for comprehensive characterization of the saponins from Xueshuantong Injection

Author:

Yang Wenzhi,Zhang Jingxian,Yao Changliang,Qiu Shi,Chen Ming,Pan Huiqin,Shi Xiaojian,Wu Wanying,Guo Dean

Funder

56th China Post-doctoral Science Foundation

National Natural Science Foundation of China

National Science and Technology Major Project for Major Drug Development

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference38 articles.

1. Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography–mass spectrometry;Wu;J. Pharm. Biomed. Anal.,2013

2. A practical strategy for the characterization of coumarins in Radix Glehniae by liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry;Yang;J. Chromatogr. A,2010

3. Identification of ginsenosides in Panax quinquefolium by LC–MS;Ma;Chromatographia,2006

4. Determination of flavonoids and saponins in Gynostemma pentaphyllum (Thunb.) Makino by liquid chromatography–mass spectrometry;Kao;Anal. Chim. Acta,2008

5. Structure characterization and identification of steroidal saponins from the rhizomes of Anemarrhena asphodeloides by ultra performance liquid chromatography and hybrid quadrupole time-of-flight mass spectrometry;Zhao;Int. J. Mass Spectrom.,2013

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