Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography–tandem mass spectrometry
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
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2. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin–drug interactions;Rettie;Chem. Res. Toxicol.,1992
3. Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance;Scordo;Clin. Pharmacol. Ther.,2002
4. Interindividual variability in sensitivity to warfarin—nature or nurture? Clin;Loebstein;Pharmacol. Ther.,2001
5. In vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosis;O'Sullivan;Clin. Pharmacol. Ther.,1993
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