N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification

Published:2017-10 Issue: Volume:145 Page:692-703
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Lu Danyi,Xie Qian,Wu Baojian

Funder

National Natural Science Foundation of China

Young Scientist Special Projects in biotechnological and pharmaceutical field of 863 Program

Outstanding Youth Fund from the Natural Science Foundation of Guangdong Province

PhD Start-up Fund of Natural Science Foundation of Guangdong Province

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference29 articles.

1. Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily;Mackenzie;Pharmacogenet. Genom.,2005

2. The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification;Rowland;Int. J. Biochem. Cell Biol.,2013

3. Roles of human UDP-glucuronosyltransferases in clearance and homeostasis of endogenous substrates, and functional implications;Bock;Biochem. Pharmacol.,2015

4. N(+)-glucuronidation of aliphatic tertiary amines, a general phenomenon in the metabolism of H1-antihistamines in humans;Luo;Xenobiotica,1991

5. Quaternary ammonium-linked glucuronidation of 1-substituted imidazoles by liver microsomes: interspecies differences and structure-metabolism relationships;Vashishtha;Drug Metab. Dispos.,2002

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Kinetic Characterization of Estradiol Glucuronidation by Liver Microsomes and Expressed UGT Enzymes: The Effects of Organic Solvents;European Journal of Drug Metabolism and Pharmacokinetics;2024-03-12

2. Inhibition of human UDP-glucuronosyltransferase enzyme by ripretinib: Implications for drug-drug interactions;Toxicology and Applied Pharmacology;2023-05

3. Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences;International Journal of Molecular Sciences;2023-01-11

4. Anastrozole and related glucuronic acid conjugate are electrophilic species;Xenobiotica;2022-04-03

5. A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation;BMC Molecular and Cell Biology;2022-01-21

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3