Development of novel chiral capillary electrophoresis methods for the serotonin receptor (5-HT2A) antagonist MDL 100,907 (volinanserin) and for its key intermediate compound

Author:

Németh Krisztina,Palkó Roberta,Kovács Péter,Visy Júlia

Funder

NANOSEN9

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference23 articles.

1. Characterization of the 5-HT2 receptor antagonist MDL 100,907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies;Sorensen;J. Pharmacol. Exp. Ther.,1993

2. Synthesis and in vitro affinities of various MDL 100,907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET;Herth;Bioorg. Med. Chem.,2009

3. [11C]MDL 100,907, a radioligand for selective imaging of 5-HT2A receptors with positron emission tomography;Lundkvist;Life Sci.,1996

4. [3H]MDL 100,907 labels 5-HT2A serotonin receptors selectively in primate brain;López-Giménez;Neuropharmacology,1998

5. M-100907 (Aventis);de Paulis;Curr. Opin. Invest. Drugs,2001

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