Combing metabolomics with bioanalysis methods to study the antitumor mechanism of the new acridone derivative 8q on CCRF-CEM cells: 8q induced mitochondrial-mediated apoptosis and targeted the PI3K/AKT/FOXO1 pathway-Reference-Cited by-同舟云学术

Combing metabolomics with bioanalysis methods to study the antitumor mechanism of the new acridone derivative 8q on CCRF-CEM cells: 8q induced mitochondrial-mediated apoptosis and targeted the PI3K/AKT/FOXO1 pathway

Published:2018-10 Issue: Volume:160 Page:314-322
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Wang Ning,Zhang Bin,Jin Feng,Gao Dan,Liu Feng,Liu Hongxia,Jiang Yuyang

Funder

National Natural Science Foundation of China

Youth Scientific Research Funds from Graduate School at Shenzhen, Tsinghua University

Reform Commission (Disciplinary Development Program for Chemical Biology)

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

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1. A comprehensive review on acridone based derivatives as future anti-cancer agents and their structure activity relationships;European Journal of Medicinal Chemistry;2022-09

2. A Novel Methoxybenzyl 5-Nitroacridone Derivative Effectively Triggers G1 Cell Cycle Arrest in Chronic Myelogenous Leukemia K562 Cells by Inhibiting CDK4/6-Mediated Phosphorylation of Rb;International Journal of Molecular Sciences;2020-07-18

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4. Biotesting of technologically important carboxy containing acridones with solid-state fungal culture;AIMS Bioengineering;2020