Quantitation of total and free teriflunomide (A77 1726) in human plasma by LC–MS/MS-Reference-Cited by-同舟云学术

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Quantitation of total and free teriflunomide (A77 1726) in human plasma by LC–MS/MS

Published:2011-05 Issue:2 Volume:55 Page:325-331
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Rakhila Halima,Rozek Tomas,Hopkins Ashley,Proudman Susanna,Cleland Les,James Michael,Wiese Michael

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference18 articles.

1. The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase;Davis;Biochemistry,1996

2. In vitro and in vivo effects of leflunomide, brequinar, and cyclosporine on pyrimidine biosynthesis;Silva;Transplant. Proc.,1997

3. Leflunomide interferes with pyrimidine nucleotide biosynthesis;Cherwinski;Inflamm. Res.,1995

4. In vivo mechanism by which leflunomide controls lymphoproliferative and autoimmune disease in MRL/MpJ-lpr/lpr mice;Xu;J. Immunol.,1997

5. Mechanism of action for leflunomide in rheumatoid arthritis;Fox;Clin. Immunol.,1999

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