Capillary isoelectric focusing method development and validation for investigation of recombinant therapeutic monoclonal antibody

Author:

Suba DávidORCID,Urbányi Zoltán,Salgó András

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference21 articles.

1. Physicochemical and functional comparability between the proposed biosimilar rituximab GP2013 and originator rituximab;Visser;BioDrugs,2013

2. Heterogeneity of monoclonal antibodies;Liu;J. Pharm. Sci.,2008

3. Structural and numerical variations of the carbohydrate moiety of immunoglobulin G;Mizuochi;J. Immunol.,1982

4. Structural heterogeneity of sugar chains in immunoglobulin G. Conformation of immunoglobulin G molecule and substrate specificities of glycosyltransferases;Fujii;J. Biol. Chem.,1990

5. Identification of multiple sources of charge heterogeneity in a recombinant antibody;Harris;J. Chromatogr. B. Biomed. Sci. Appl.,2001

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