UHPLC-MS-Based Lipidomic and Metabonomic Investigation of the Metabolic Phenotypes of Wild Type and Hepatic CYP Reductase Null (HRN) Mice
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference16 articles.
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2. The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: application to the metabolism of diclofenac;Pickup;Xenobiotica,2012
3. Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild–type mice;Akingbasote;Arch Toxicol.,2016
4. The hepatic cytochrome P450 reductase null mouse as a tool to identify a successful candidate entity;Henderson;Toxicol Lett.,2006
5. Global metabolic profiling of animal and human tissues via UPLC-MS;Want;Nature Protocols,2013
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis;Frontiers in Pharmacology;2021-11-15
2. Proteomic consequences of the deletion of cytochrome P450 (CYP450) reductase in mice;Journal of Chromatography B;2021-08
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