Isolation and structure characterization of related impurities in etimicin intermediate P1 by LC/ESI–MSn and NMR

Author:

Wang Yuanchao,Zhang Zhijie,Wu Lingyun,Zhang Xiaoqi,Wang Hao,Ye Wencai,Li Ping

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference14 articles.

1. Synthesis and structure determination of semisynthetic antibiotic 89-07;Fan;Chin. J. Antibiot.,1995

2. Comparison of clinical efficacy and safety between etimicin and netilmicin in treatment of bacterial infections in lower respiratory tract;lan;Chin. J. New Drugs Clin. Rem.,2004

3. Ototoxicity of etimicin. III. Comparison of the ototoxic effects of etimicin on vestibular function with those of gentamicin and amikacin;Shi;Chin. J. Antibiot.,1999

4. Sub-acute toxicity study of a new aminoglycoside etimicin sulphate in Swiss albino mice;Payasi;J. Toxicol. Sci.,2010

5. Semisynthetic 1-N-ethylgentamiein C1a and method for its preparation;Zhao;US Patent 5,814,488,1998

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