A LC/MS/MS micro-method for human plasma quantification of vemurafenib. Application to treated melanoma patients

Author:

Alvarez Jean-Claude,Funck-Brentano Elisa,Abe EmuriORCID,Etting Isabelle,Saiag Philippe,Knapp Adeline

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference10 articles.

1. Mutations of the BRAF gene in human cancer;Davies;Nature,2002

2. Inhibition of mutated activated BRAF in metastatic melanoma;Flaherty;N. Engl. J. Med.,2010

3. Improved survival with vemurafenib in melanoma with BRAF V600E mutation;Chapman;N. Engl. J. Med.,2011

4. Vemurafenib: a new treatment for BRAF-V600 mutated advanced melanoma;Fischer;Cancer Manage. Res.,2012

5. Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia;Picard;Blood,2007

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