Structural characterization of low level degradants in aztreonam injection and an innovative approach to aid HPLC method validation

Author:

Ye Qingmei,Ding Wei,Rinaldi Frank,Huang Yande,Miller Scott A.,Bolgar Mark

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference12 articles.

1. Food and Drug Administration, Guidance for Industry #5: Drug Stability Guidelines, 2008.

2. Chemical Stability of Pharmaceuticals;Pipkin,1986

3. Photodegradation kinetics under UV light of aztreonam solutions;Fabre;J. Pharm. Biomed. Anal.,1992

4. Photodegradation paths of cefotaxime;Lerner;J. Pharm. Sci.,1988

5. Compatibility and stability of aztreonam and vancomycin hydrochloride;Trissel;Am. J. Health Syst. Pharm.,1995

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