Determination of tramadol and metabolites by HPLC-FL and HPLC–MS/MS in urine of dogs

Author:

Saccomanni G.,Del Carlo S.,Giorgi M.,Manera C.,Saba A.,Macchia M.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference28 articles.

1. Clinical pharmacology of tramadol;Grond;Clin. Pharmacokinet.,2004

2. Biotransformation of tramadol in man and animal;Lintz;Arzneimittelforschung,1981

3. Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes;Subrahmanyam;Drug Metab. Dispos.,2001

4. Pharmacokinetics of tramadol and O-desmethyltramadol in goats after intravenous and oral administration;de Sousa;J. Vet. Pharmacol. Ther.,2008

5. Pharmacokinetics of tramadol, and its metabolite O-desmethyl-tramadol, in cats;Pypendop;J. Vet. Pharmacol. Ther.,2008

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