Development, validation and application of a novel liquid chromatography tandem mass spectrometry assay measuring uracil, 5,6-dihydrouracil, 5-fluorouracil, 5,6-dihydro-5-fluorouracil, α-fluoro-β-ureidopropionic acid and α-fluoro-β-alanine in human plasma-Reference-Cited by-同舟云学术

Development, validation and application of a novel liquid chromatography tandem mass spectrometry assay measuring uracil, 5,6-dihydrouracil, 5-fluorouracil, 5,6-dihydro-5-fluorouracil, α-fluoro-β-ureidopropionic acid and α-fluoro-β-alanine in human plasma

Published:2017-08 Issue: Volume:142 Page:125-135
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Chavani Ottiniel,Jensen Berit Packert,Strother R. Matthew,Florkowski Christopher M.,George Peter M.

Funder

Milos Hroch

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference39 articles.

1. 5-Fluorouracil derivatives: a patent review;Alvarez;Expert Opin. Ther. Pat.,2012

2. Pharmacokinetically guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes;Saif;J. Natl. Cancer Inst.,2009

3. Clinical impact of pharmacokinetically-guided dose adaptation of 5-fluorouracil: results from a multicentric randomized trial in patients with locally advanced head and neck carcinomas;Fety;Clin. Cancer Res.,1998

4. Role of body surface area in dosing of investigational anticancer agents in adults, 1991–2001;Baker;J. Natl. Cancer Inst.,2002

5. Pharmacokinetic variability of anticancer agents;Undevia;Nat. Rev. Cancer,2005

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploring the ethnopharmacological significance of Cynara scolymus bracts: Integrating metabolomics, in-Vitro cytotoxic studies and network pharmacology for liver and breast anticancer activity assessment;Journal of Ethnopharmacology;2024-11

2. Partial protein binding of uracil and thymine affects accurate dihydropyrimidine dehydrogenase (DPD) phenotyping;Journal of Pharmaceutical and Biomedical Analysis;2024-10

3. Comparison between a single- and a multi-point calibration method using LC-MS/MS for measurement of 5-fluorouracil in human plasma;Journal of Mass Spectrometry and Advances in the Clinical Lab;2024-08

4. Short-term biological variation of plasma uracil in a Caucasian healthy population;Clinical Chemistry and Laboratory Medicine (CCLM);2023-03-02

5. Quantification of uracil, dihydrouracil, thymine and dihydrothymine for reliable dihydropyrimidine dehydrogenase (DPD) phenotyping critically depend on blood and plasma storage conditions;Journal of Pharmaceutical and Biomedical Analysis;2022-11