Identification of a drug degradation product found in a stressed dosage form using LC/MSn, LC/TOF MS and on-line H/D exchange MS-Reference-Cited by-同舟云学术

Identification of a drug degradation product found in a stressed dosage form using LC/MSn, LC/TOF MS and on-line H/D exchange MS

Published:2012-01 Issue: Volume:57 Page:99-103
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Pan Changkang,Jiang Yanjing,Wen Hong,Motto Michael

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference5 articles.

1. Guidance for Industry, Q3B Impurities in New Drug Products;U.S. Food and Drug Administration,2006

2. Stress testing: a predictive tool;Baertschi,2005

3. Stress testing: analytical considerations;Jansen,2005

4. Analysis of impurities and degradants in pharmaceuticals by high resolution tandem mass spectrometry and on-line H/D exchange LC/MS;Chen;Am. Pharm. Rev.,2010

5. Identification and characterization of a photolytic degradation product of telmisartan using LC–MS/TOF, LC–MSn, LC–NMR and on-line H/D exchange mass studies;Shah;J. Pharm. Biomed. Anal.,2010

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