LC-MS/MS-based metabolite quantitation of the antiviral prodrug baloxavir marboxil, a new therapy for acute uncomplicated influenza, in human plasma: Application to a human pharmacokinetic study

Author:

Gouda Amira S.,Abdel-Megied Ahmed M.,Rezk Mamdouh R.,Marzouk Hoda M.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference16 articles.

1. CDC, Influenza Antiviral Drug Baloxavir Marboxil, 2021. 〈https://www.cdc.gov/flu/treatment/baloxavir-marboxil.htm〉.

2. Baloxavir marboxil: a review in acute uncomplicated influenza;Shirley;Drugs,2020

3. 〈https://pubchem.ncbi.nlm.nih.gov/compound/Baloxavir-marboxil〉, (Accessed 4 June 2022).

4. 〈https://pubchem.ncbi.nlm.nih.gov/compound/Baloxavir〉, (Accessed 4 June 2022).

5. Safety, tolerability, and pharmacokinetics of the novel anti-influenza agent baloxavir marboxil in healthy adults: phase I study findings;Koshimichi;Clin. Drug Investig.,2018

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