Forced degradation studies of elagolix sodium with the implementation of high resolution LC-UV-PDA-MSn (n = 1,2,3…) and NMR structural elucidation

Author:

Zhong Xueni,Lv Qianqian,Yong Qiyun,Hu Wenping,Li Dan,Ji Shuhui,Zhan Liuyue,Chen Wenbin,Li Min,Lin Jinsheng,Sun Cuirong

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference25 articles.

1. Impurities and forced degradation studies: a review;Kogawa;Curr. Pharm. Anal.,2016

2. ICH Q1A (R2). Stability testing of new drug substances and products, published in November 2003.

3. Development of forced degradation and stability indicating studies of drugs-a review;Blessy;J. Pharm. Anal.,2014

4. Endometriosis: pathogenesis and treatment;Vercellini;Nat. Rev. Endocrinol.,2014

5. Overview of elagolix for the treatment of endometriosis;Melis;Expert Opin. Drug Metab. Toxicol.,2016

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