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Qualitative and quantitative studies on human B7.1-Fc fusion protein and the application in pharmacokinetic study in rhesus monkeys

  • Published:2011-01 Issue:1 Volume:54 Page:133-140
  • ISSN:0731-7085
  • Container-title:Journal of Pharmaceutical and Biomedical Analysis
  • language:en
  • Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Chen Zhihang,Liu Ruorui,Che Jinjing,Shi Hongjiao,Hou Yunan,Liu Yunlong,Sun Lili,Tan Li,Shan Chengqi,Hu Peisheng,Cheng Yuanguo

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference27 articles.

1. The CD28 ligand, B7, enhances IL-2 production by providing a costimulatory signal to T cells;Norton;J. Immunol.,1992

2. CD28–B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help;Harding;J. Exp. Med.,1993

3. CD28-mediated signaling co-stimulates murine T cells and prevents induction of energy in T-cell clones;Harding;Nature,1992

4. CD28/B7 system of T cell costimulation;Lenschow;Annu. Rev. Immunol.,1996

5. Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28;Metzler;Nat. Struct. Biol.,1997

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