A validated LC–MS/MS assay for the simultaneous determination of periplocin and its two metabolites, periplocymarin and periplogenin in rat plasma: Application to a pharmacokinetic study

Author:

He Jun,Bo Fang,Tu Yaru,Azietaku John Teye,Dou Ting,Ouyang Huizi,Chang Yanxu,Liu Hong,Gao Xiumei

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference14 articles.

1. Gene expression profiling of the proliferative effect of periplocin on mouse cardiac microvascular endothelial cells;Wang;Chin. J. Integr. Med.,2010

2. Inhibition of periplocin on human hepatoma carcinoma and breast carcinoma cells in vitro;Ding;Drug Eval. Res.,2014

3. Antitumor effect of periplocin in TRAIL-Resistant human hepatocellular carcinoma cells through downregulation of IAPs;Cheng;Evid-based Compl. Alt.,2013

4. Periplocin from Cortex periplocae inhibits cell growth and down-regulates survivin and c-myc expression in colon cancer in vitro and in vivo via ß-catenin/TCF signaling;Zhao;Oncol. Rep.,2010

5. Comparative proteomic analysis of anti-cancer mechanism by periplocin treatment in lung cancer cells;Lu;Cell. Physiol. Biochem.,2014

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