Development of a simple and rapid method to determine the unbound fraction of dolutegravir, raltegravir and darunavir in human plasma using ultrafiltration and LC–MS/MS

Author:

Zheng Yi,Lui Gabrielle,Boujaafar Sana,Aboura Radia,Bouazza Naïm,Foissac Frantz,Treluyer Jean-Marc,Benaboud Sihem,Hirt Déborah,Gana Inès

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference25 articles.

1. Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis;Kanters;Lancet HIV,2016

2. Raltegravir: a review of its pharmacokinetics, pharmacology and clinical studies;Burger;Expert Opin. Drug Metab. Toxicol.,2010

3. Dolutegravir – a review of the pharmacology, efficacy, and safety in the treatment of HIV;Kandel;Drug Des. Devel. Ther.,2015

4. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV;DHHS,2018

5. Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach;WHO,2016

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