Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin, artemether and dihydroartemisinin in rats

Author:

Dai Tianming,Jiang Weifan,Guo Zizheng,Xie Yanxiang,Dai Renke

Funder

Guangdong Science and Technology Planning Founding

Guangdong Province High-tech Industry Development Zone

Zhongshan Introducing Talent Award

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference24 articles.

1. Artemisinin-based combination therapies for uncomplicated malaria;Davis;Med. J. Aust.,2005

2. Artemisinins: artemisinin, dihydroartemisinin, artemether and artesunate, milestones;Karunajeewa;Drug Ther.,2011

3. Differential effects of orally versus parenterally administered qinghaosu derivative artemether in dogs;Classen;Exp. Toxicol. Pathol.,1999

4. Uptake of [3h] dihydroartemisinine by erythrocytes infected with plasmodium falciparum in vitro;Gu;T. Roy. Soc. Trop. Med. H.,1984

5. Determination of artemether in plasma and whole blood using hplc with flow-through polarographic detection;Huang;Biomed. Chromatogr.,1987

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